The study highlights the crucial role of succinyl-CoA in tumor immunity by inducing the succinylation of PD-L1. We identified the succinyltransferase CPT1A as a potential therapeutic target.

According to the COA report, UP Baguio left over P100 million in General Appropriations Act (GAA) funds unused between 2018 and 2023. But funding requests for student activities had been denied ...

Through the generated simulations, we have shown that KB concentration levels rise during prolonged starvation, and in consideration of glucose hypometabolism, MCT-induced intervention increases the ...

Graduate Institute of Environmental Engineering, National Central University, Taoyuan 32001, Taiwan (R.O.C.) Department of Chemical and Materials Engineering ...

The Commission on Audit (CoA) has passed an international standards assessment of its methodologies and earned an Independent Review Statement. The commission said that it completed a repeat ...

This study reveals that PRMT1 overexpression drives tumorigenesis of acute megakaryocytic leukemia (AMKL) and that targeting PRMT1 is a viable approach for treating AMKL. While the evidence, based ...

Here, we examined the effect of different carbon sources that are involved in the major metabolic pathways of acetyl-CoA synthesis on myocardial infarction and found that elevation of acetyl-CoA by ...