Ten patients with marked hemolytic anemia secondary to prosthetic cardiac valve replacement are presented. Although the etiology of this disorder is not understood, available evidence supports the ...

Elevated plasma levels of Lp(a) [lipoprotein(a)] are a causal risk factor for coronary heart disease and stroke in European individuals, but the causal relevance of Lp(a) for different stroke types ...

High-quality mechanistic and clinically relevant science to keep clinicians at the forefront of the latest advancements in the diagnosis and treatment of heart failure ...

To address this question in detail, one must first have an accurate map of the diverse patterns of investment by SMC ...

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Background: Intramural site of origin is a major cause of ablation failure of ventricular arrhythmias and the optimal strategy is unclear. This study investigated the efficacy of a stepwise ablation ...

Background: The PRAETORIAN trial investigated the efficacy and safety of the subcutaneous implantable cardioverter-defibrillator (S-ICD) compared with transvenous ICD (TV-ICD) and showed ...

Background: There is sparse high-quality safety and effectiveness data for pulsed field ablation (PFA) of persistent atrial fibrillation (PerAF), where lesions beyond pulmonary vein isolation (PVI) ...

LBBP is defined as capturing the left bundle branch (LBB) trunk or its fascicles, whereas capturing only the left septal ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

BACKGROUND: High-volume physical activity (PA) is associated with a higher prevalence of subclinical coronary artery disease ...