Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

Burn and Plastic Surgery, Central People’s Hospital of Zhanjiang, Zhanjiang, China Pre-screening Triage in Outpatient Department, Central People’s Hospital of Zhanjiang, Zhanjiang, China ...

TABLE 1. Factors regulating odontoblastic differentiation via signaling pathways. Nevertheless, there is still conflict regarding the role of Wnt/β-catenin signaling in odontoblast differentiation.

Wnt signaling plays important roles in development, homeostasis, and tumorigenesis. Mutations in β-catenin that activate Wnt signaling have been found in colorectal and hepatocellular carcinomas.

Disruptions to developmental cell signaling pathways and transcriptional cascades have been ... SHH, bone morphogenetic proteins (BMPs), WNT ligands, NOTCH ligands, chordin (CHRD), Hippo signaling ...

BCL9 and PYGO are β-catenin cofactors that enhance the transcription of Wnt target genes. They have been proposed as therapeutic targets to diminish Wnt signaling output in intestinal malignancies.