The aberrant expression of partner of NOB1 homolog (PNO1) is known to promote oncogenesis in the colorectum and the esophagus, but its involvement in ovarian cancer and the mechanisms behind it are ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

Gene set enrichment analysis (GSEA) showed that WNT signaling, cell cycle, p53, and apoptotic pathways ... catenin from phosphorylation-dependent proteasome degradation by β-TrCP (F-box protein ...

Beta catenin meanwhile is a signalling protein in the Wnt/Wingless pathway – in particular a downstream transcription factor (TCF) implicated in a range of solid tumour types including ...