Fungal infections are on the rise globally. According to a study by the Manchester Fungal Infection Group, in 2022, ...

a phenomenon called RNA interference or RNAi. The apparently widespread nature of RNAi in eukaryotes, ranging from trypanosome to mouse, has sparked great interest from both applied and ...

In 1998, Andrew Fire and Craig Mello published a groundbreaking study demonstrating that double-stranded RNA (dsRNA) could silence genes in the nematode Caenorhabditis elegans. This discovery laid the ...

View Full Profile. Learn about our Editorial Policies. The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi ...

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of ...

Efficient RNA interference in Caenorhabditis elegans requires a distinct class of secondary short interfering RNA. Although many proteins involved in RNAi were initially studied in the context of ...

RNA interference (RNAi) is a cellular mechanism that uses small RNA molecules, such as small interfering RNAs (siRNAs) and miRNAs, to silence gene expression. These small RNAs can bind to ...

RNAi – functions specifically to silence, or deactivate, genes. Among other applications, it promises to be groundbreaking as ...