Figure 5: Parkin exhibits ubiquitination activity in vitro. Parkin consists of two functionally different domains (Fig. 6): the C-terminal RING-box, which recruits a specific E2 enzyme (UbcH7 ...

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

Enzymes are present in microorganisms, plants and animals and act as catalysts in various chemical reactions. This means that they increase the rate of the reactions. Because of this they can be ...

Luckily, there are supplements containing the lactase enzyme available which aid in lactose breakdown in the small intestine, providing potential relief. When searching for the best lactase enzyme ...

The breakthrough came with a small but powerful idea. They introduced goose lipases – natural enzymes used by birds to break down fat in their digestive systems. These enzymes had never been used in ...

"The TDP-43 aggregates induced by the fibrils exhibited many of the modifications we also see in patient brains, including phosphorylation and ubiquitination. Strikingly, the aggregates were able ...

S.W. Chung and J.S. Kim equally contributed to this article as co-first authors. W.-M. Choi and K.M. Kim equally contributed to this article as co-corresponding authors.

Digestive enzymes play a crucial role in breaking down food and ensuring the body absorbs essential nutrients efficiently. Without these enzymes, even the healthiest diet may not provide the full ...

About 98% of lignin created as a forestry by-product from plants is discarded, but a new enzyme could be the key to extracting high-value molecules from this waste using a green chemistry approach.

4,5 Belonging to the serine protease family, these enzymes proteolytically activate the zymogen plasminogen to plasmin, the primary fibrinolytic enzyme. This review examines the roles of PAs in the ...