“We’re excited to share these enzymes with the genome editing community and to get feedback on their performance as nucleases, base editors, and as other genome editing modalities,” said ...

In their study, authors developed a machine learning algorithm-known as PAMmla-that can predict the properties of about 64 million genome editing enzymes. The work could help reduce off-target ...

When it comes to absorption, digestive enzymes are crucial. “The best digestive enzymes, whether natural or in supplemental form, help ensure your food is properly broken down so your body can ...

By targeting this enzyme, we can develop more effective treatments for glioblastoma, a brain tumor with very few effective treatment options," said study lead author Deliang Guo, Ph.D., the ...

Decreased activity of the enzyme ELOVL2 accelerates white blood cell aging and alters the expression of cancer-associated genes, new research suggests. Image depicts immune cells in the bone marrow, ...

Newco Brink Therapeutics SAS is poised to work on the next chapter in genome editing after raising €3.5 million (US$4 million) in seed funding to discover and develop programmable recombinase enzymes.

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Academy of Sciences, Nanning 530007, China ...

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China Key Laboratory of Pharmaceutical Engineering of ...

SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease. Molecular Neurodegeneration , 2025; 20 (1) DOI: 10.1186/s13024-024-00788-8 Cite This Page : ...