The EMBO Journal15h
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
Human genetics provides clues to why DNA regulatory regions get 'loopy'
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
C&EN18d
Design and Synthesis of Topoisomerases-Histone Deacetylase Dual Targeted Quinoline-Bridged Hydroxamates as Anticancer Agents
Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Pharmaceutical Sciences, Central University of Punjab, Bathinda 151 401, India ...
Live Science27d
How do DNA tests tell if two people are related?
How can DNA from a cheek swab determine if someone is closely related to you? When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. DNA tests can ...
Healio29d
Phase 3 data show potential of new oral treatments for gonorrhea
Gepotidacin is a new triazaacenaphthylene antibiotic that selectively inhibits bacterial DNA replication by interacting ... and the parC subunit of bacterial topoisomerase IV.