If empirical treatment of patients with chronic constipation fails, osmotic laxatives (e.g. lactulose and polyethylene glycol), a serotonin (5-HT 4) receptor agonist (e.g. tegaserod) or a chloride ...

The US Food and Drug Administration (FDA) convenes public advisory committee meetings to address issues in new drug applications (NDAs), biologics license applications (BLAs), or clinical trials ...