Centre of Biomolecular Drug Research, Leibniz University Hannover, Schneiderberg 38, Hannover 30167, Germany Department of Applied Bioinformatics, Institute for Microbiology and Genetics, University ...

The Squalene market is driven by rising demand in cosmetics, pharmaceuticals, and dietary supplements due to its antioxidant and anti-aging properties. Europe dominates due to strict regulations ...

2015) (NCT01831232). Oxide squalene cyclase (OSC) is the enzyme that catalyzes the conversion of a 2,3-monoepoxy squalene to a lanosterol. Since lanosterol is a precursor to cholesterol, inhibition of ...

We previously showed that the rate-limiting and first oxygen-dependent enzyme of the committed cholesterol synthesis pathway, squalene monooxygenase (SM), can undergo partial proteasomal degradation ...

Yeasts are promising industrial hosts for sustainable production of fuels and chemicals. Apart from efficient bioethanol production, yeasts have recently demonstrated their potential for biodiesel ...