When the Galej Group started the project, little was known about the minor spliceosome, and even now, only a handful of research groups are doing structural studies on this RNA-protein complex.

When the Galej Group started the project, little was known about the minor spliceosome, and even now, only a handful of research groups are doing structural studies on this RNA-protein complex.

New findings on gene regulation In addition, it was shown that insulin influences the function of the so-called spliceosome complex, a key regulatory element of gene regulation. This suggests that ...

They succeeded once they were able to isolate the splicing complexes of the fungus that were in the midst of quality control ...

On the other hand, this protein is part of the spliceosome, a molecular complex that modifies RNA before it is translated into proteins.

Aided by two molecular control factors, the spliceosome rejects pre-mRNA that could be incorrectly spliced. While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...