News

C&EN7h
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction | ACS Medicinal Chemistry Letters - ACS Publications
The NRF2-ARE pathway is an intrinsic mechanism of defense against oxidative stress. Inhibition of the interaction between NRF2 and its main negative regulator KEAP1 is an attractive strategy toward ...
C&EN23h
Small Peptides Catalyze Highly Enantioselective Direct Aldol Reactions of Aldehydes with Hydroxyacetone: Unprecedented Regiocontrol in Aqueous Media | Organic Letters
l-Proline-based small peptides have been developed as efficient catalysts for the asymmetric direct aldol reactions of hydroxyacetone with aldehydes. Chiral 1,4-diols 7, which are disfavored products ...
Why is there a giant ‘P' on SLO hill? An ‘M'? Learn stories behind iconic initials
Here are the origin stories behind some of the hillside landmarks. Where did the Cal Poly ‘P' come from? The Cal Poly "P" is ...
The Joplin Globe4d
LongWater Completes First SBIC Fund Investment with Valley Lighting
LongWater is pleased to announce its investment in Valley Lighting, a provider of commercial lighting and shading solutions based in Linthicum Heights, Maryland. The investment marks the first ...