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G protein–coupled receptors (GPCRs), also known as seven-transmembrane receptors, are the largest family of plasma membrane receptors (∼ 1,000 members) and the most important class of targets ...

The Interdisciplinary Genitourinary Cancer Forum 2025, held between June 19 – 21, 2025 held in St. Petersburg, Florida, United States, was host to the Prostate Cancer Session 7: Non-metastatic ...

EM, researchers elucidated the structure of key receptors integral to fast excitatory synaptic transmission in the rat cerebellum.

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...

Among the 7MM, Japan accounts for the second highest total aplastic anemia drugs market. The Aplastic Anemia Treatment Market ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

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P2Y 12 is a Gi-coupled 7-transmembrane domain receptor, which mediates platelet activation by inhibiting an AC-mediated signaling pathway and decreasing the cAMP intracellular levels. It also ...

The impact of PTEN deletion, TMPRSS2:ERG fusion, and androgen receptor variant 7 (AR-V7) on resistance to novel hormone therapies (NHTs) in castrate-resistant prostate cancer. Daria Yakimova , ...