A team of international researchers led by scientists at City of Hope®, one of the largest and most advanced cancer research ...

Research Progress on Signaling Pathways of LGALS1 in Malignant Tumors. Journal of Biosciences and Medicines, 13, 142-155. doi: 10.4236/jbm.2025.136013 . Malignant tumors, commonly referred to as ...

the study uncovers a new regulatory role for a type of protein domains common in many nuclear proteins, but until now only poorly understood. The IDR in TAF2 steers the protein away from active ...

Abstract: Structural domains are evolutionary and functional units of proteins and play a critical role in comparative and functional genomics. Computational assignment of domain function with high ...

“However, protein domains from plants and light-responsive microbes can be synthetically incorporated into organisms that normally don’t respond to light. In this way, proteins can be engineer ...

Scientists have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to better understand the role of this protein domain ...

BTB (bric-a-brack, Tramtrack, and broad complex) is a diverse group of protein-protein interaction domains found within metazoan proteins. Transcription factors contain a dimerizing BTB subtype with a ...

Find more information on the Altmetric Attention Score and how the score is calculated. With the development of deep learning, almost all single-domain proteins can be predicted at experimental ...

The protein domain that is responsible for the recognition of collagen has previously been mistaken for a subform of another. Dr. Oliver Arnolds and Professor Raphael Stoll from the Faculty of ...

The majority of proteins in nature are composed of multiple domains connected in a single polypeptide. How these long sequences fold into functional structures without forming toxic misfolds or ...