C5a receptors, specifically C5aR1 and C5aR2, are critical components of the innate immune system ... receptors (PRRs): Proteins on immune cells that recognize pathogens and initiate immune ...

The discovery of microbial-sensing proteins called Toll-like receptors ... innate immune response lasts too long. The adaptive response, on the other hand, generates antibody-secreting B cells ...

Innate immune cells exhibit rapid cytotoxic activity ... The T-cells and B-cells in this system have receptors that recognize specific foreign antigens, and they develop long-lasting immune ...

It’s a common, straightforward idea in science: When a viral, bacterial, or parasitic pathogen sneaks its way into a host and tries to infect cells, the immune system detects ... insight into how ...

Our cells need to be able to recognize potential invaders as a threat, the key function of the body's innate immune system. Sometimes this process fails, causing the body to react to its own cells ...

The bottom line is that the recognition of different Gram-negative and -positive microbes involves different TLR receptors ... signatures by cells of the innate immune system.

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from ... striking was that the innate immune system ...

The system relies on innate immune sensors to detect and transmit signals about these threats. One of the key innate immune strategies to respond to threats is through cell death. New research ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

Professor Meghan Morrissey earns an innovation award to program immune cells to attack cancer tumors. #immunotherapy ...

In this review, we examine host-pathogen interactions through the Toll-like receptors and Nod signaling systems as principal mechanisms of the innate immune response, and explore the application ...