Research team developed PathActMarker, a software package for pathway activity inference and analysis. It preprocesses gene ...

A team of Singapore scientists has made a significant discovery in understanding stomach cancer, a disease that remains one ...

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting the expression or function of Piezo2, a receptor that senses mechanical ...

Researchers have found a potential new way to slow the progression of lung fibrosis and other fibrotic diseases by inhibiting ...

PARP7 is a mono-ADP-ribosyl transferase (mono-ART) which has recently gained attention due to its emerging role as a negative ...

Maximum mean reduction in serum AH50 (alternative pathway hemolytic assay) of 85% and mean sustained reduction greater than 76%. Maximum mean reduction in Wieslab AP (alternative pathway ...

Arrowhead Pharmaceuticals’ phase 1/2a study has found the company’s investigational RNA interference (RNAi) candidate was generally well tolerated among 14 patients with kidney disease.

Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing. This news release contains forward-looking statements within the meaning of the "safe harbor" provisions of ...

The presentation titled, "Targeting Obesity with RNAi-based Therapies," was included ... both seek to intervene in a known biological pathway with strong support from human genetics studies ...

Furthermore, the TP53 pathway, a crucial tumor suppressor mechanism ... including the inhibition of exosomal RNA-mediated tumor progression and the utilization of engineered exosomes for targeted ...

Homocysteine is not recycled back to methionine, but is further metabolized in the transsulfuration pathway. Interestingly, our data suggest an alternative link between methionine and CTH independent ...