Small interfering RNA are double-stranded RNA molecules most notably involved in the RNA interference (RNAi) pathway where they interfere with gene expression by targeting specific mRNA for ...

Scientists at the University of Toronto studying the hermaphroditic worm Caenorhabditis elegans found that amyloid-like ...

interferon pathway machinery) or nontargeted mRNAs. As a result, the standard of care to demonstrate the specificity of an observed RNAi-induced phenotype (namely the suppression of the targeted ...

siRNA: short strands of RNA that are also part of the RNA interference pathway, however, are specific to a single target mRNA. Also includes antisense oligonucleotides (ASO). Antisense ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent ...

In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases.

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United States.

Unlike animals, plants do not possess an adaptive immune system with antibodies or T cells to fight viral infections. Instead, they rely on the RNA silencing system, which serves as their innate ...

A new study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National ...

Hepatocellular carcinoma (HCC) is a primary liver cancer that often occurs in patients with non-viral chronic liver disease ...