To understand how RNA functions, it is essential for scientists to know its 3D structure. Kihara studies protein tertiary structure prediction/comparison, protein-protein docking, protein-ligand ...

Reference: Kagaya Y, Zhang Z, Ibtehaz N, et al. NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation. Nat Commun. 2025;16(1):881. doi: ...

the researchers concluded that the Fabs were recognizing the tertiary RNA structure, not just a linear epitope. The recognition was also extremely specific. Kossiakoff and Koide have been ...

RNA tertiary structure motifs, macromolecular structure, molecular evolution, machine learning in bioinformatics (neural nets, support vector machines). RNA plays a wide range of previously ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...

What have we learned about RNA structure and function so far? Although RNA is a single-stranded molecule, researchers soon discovered that it can form double-stranded structures, which are ...