The FDA has accepted GSK’s New Drug Application (NDA) for linerixibat, a potential first-in-class IBAT inhibitor, for the treatment of cholestatic pruritus in patients with primary biliary cholangitis ...

The itching, known medically as pruritus, was so bad that affected people described “significant and persistent impact on quality of life and ability to function.” ...

Cases of pruritus have been reported in long-term users of cetirizine and levocetirizine following discontinuation of the allergy medications.

GSK plc announced positive results from the GLISTEN phase III trial evaluating linerixibat, an investigational targeted inhibitor of the ileal bile acid transporter (IBAT), in adults with cholestatic ...

Common causes of itchy testicles (pruritus scroti) are poor hygiene, fungal infections, chafing, and certain sexually transmitted infections (STIs).

Detomidine is under clinical development by Clexio Biosciences and currently in Phase II for Pruritus.

GSK plc announced positive headline results of GLISTEN, the ongoing global phase III clinical trial evaluating linerixibat, an investigational targeted inhibitor of the ileal bile acid transporter ...

Linerixibat improved cholestatic pruritus in patients with primary biliary cholangitis, according to phase 3 trial results.

Pruritus simply means itching. It can be associated with several disorders, including dry skin, skin disease, pregnancy, and rarely, cancer. An itch may be confined to just one part of your body ...

Pruritus, or “itchy skin,” also affects patients with nondialysis chronic kidney disease (CKD) and is tied with worse outcomes.

Meeting Coverage > AASLD PPAR Agonist Led to 'Clinically Meaningful' Improvement in PBC-Related Pruritus — Seladelpar also improved markers of disease activity versus placebo by Mike Bassett ...

Moderate to severe pruritus remains a chronic problem in patients on maintenance hemodialysis that can reduce overall quality of life, according to recently published data. Investigators led by ...