F.-U. Hartl, W. Neupert, "Protein sorting to mitochondria: evolutionary conservations of folding and assembly," Science, 247:930-38, 1990. Franz-Ulrich Hartl (University of Munich, Germany): "In this ...

The pinching off of the membrane vesicle (not shown) is initiated by a targeted redistribution of proteins (sorting, right).

Endosomes play a vital role in the sorting and delivery of proteins and lipids within cells. Dr. Turer co-led the study with Ezra Burstein, M.D., Ph.D., Professor of Internal Medicine and Chief of ...

For this reason, eukaryotic cells have evolved complex sorting machineries to ensure the dynamic and strictly controlled flow of proteins between cellular compartments. This machinery exists in ...

Defects in endosomal proteins are known to be associated with neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease (AD). Sorting Nexin proteins are a diverse family of ...

Previous research indicated that a protein called sorting nexin 17 (SNX17) and a protein complex called Retriever are pivotal to this recycling process, but how they work together has been unclear. To ...