Researchers have developed an inexpensive blood test that they say can detect pancreatic cancer — even in its early stages.

Cytonics, an early-stage biopharmaceutical company developing therapies for osteoarthritis, today announced that the last ...

“Production of proteases is a hallmark of cancer progression and circulating protease activity may inform diagnosis of certain cancers,” researchers wrote in the journal, Science Translational ...

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post ...

The study demonstrates that PAC-MANN-1 outperforms the widely used CA 19-9 biomarker, offering greater accuracy in detecting all stages of PDAC. The assay is particularly promising for identifying ...

Pathogens can produce analogous proteases to subvert the host immune response. The balance in activity between a protease and its inhibitor can tune the immune response or cause damage as a result ...

In recent study, PAC-MANN identified pancreatic ductal adenocarcinoma samples with 98 percent specificity and 73 percent sensitivity across all stages.

and its second immunoglobulin protease pipeline candidate engineered to have potent enzymatic activity with optimized therapeutic properties. The in vitro and in vivo data supporting S‑8484 are ...