One ring to bind them all. Using state-of-the-art cryo-electron microscopy, the research team was able to decipher the structure.To do this, the membrane proteins were shock-frozen in a solution ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo ...

When the antibiotic bedaquiline was introduced in 2012, it was the first new tuberculosis drug in over 40 years. Bedaquiline ...

Researchers from the Institute of Modern Physics (IMP) of the Chinese Academy of Sciences (CAS), together with collaborators ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

Numerous studies have indicated that the plasma membrane plays an important role in the development of resistance to anthracycline and vinca alkaloid drugs (pleiotropic resistance). We have ...

Vivid plasma separation membranes are optimized for one-step plasma separation from whole blood without the need for centrifugation. Whole blood processed through the Vivid plasma separation membrane ...

Membrane chromatography offers a promising solution for streamlining antibody purification, ... R. Modelling the Mass Transfer of a Polysaccharide-Based Protein A Chromatography Membrane with a ...

Ligand binding to membrane proteins may be significantly influenced by the interaction of ligands with the membrane. In particular, the microscopic ligand concentration within the membrane surface ...