The products of the cytochrome P450 (CYP) genes play an ... mediates the well studied induction of CYP2B10 gene expression by phenobarbital (PB) and 1, 4-bis-[2-(3, 5,-dichloropyridyloxy)] benzene ...

Although the results of the present study strongly suggest that the lowering of serum bilirubin concentration by phenobarbital in the hyperbilirubinemic infant was due to induction of a ...

What is phenobarbital used for? Phenobarbital is commonly used as a sedative (to cause drowsiness) or to control certain types of seizures. Phenobarbital may also be used for other conditions as ...

It is now recognized that reduced 25-hydroxyvitamin D levels may result from the up-regulation of the hepatic cytochrome P450 enzymes by anticonvulsant inducers, such as phenobarbital, phenytoin, and ...

There are several microsomal enzymes, including flavin monooxygenases, cytochrome P450, NADPH cytochrome c ... system can be activated by using an inducer drug that can bind to the receptor ...