protein receptor-binding domain (RBD) chimeric from different lineages fused with Fc fragments. Results: In mice and non-human primates, RBDco effectively induced neutralizing antibodies against ...

Attribution (BY): Credit must be given to the creator. Immunoreagents, most commonly antibodies, are integral components of lateral flow immunoassays. However, the use of antibodies comes with ...

HMI-115 is a monoclonal antibody that works by blocking the prolactin receptor (PRLR). The endometrium has this ... which ultimately leads to more production of proinflammatory prostaglandin E2 (PGE2) ...

1 School of Sports Health, Shenyang Sport University, Shenyang, Liaoning, China 2 College of Sport Science, Zhuhai College of Science and Technology, Zhuhai, Guangdong, China SWELL1 is a key component ...

To date, the brain PK of bAbs that target transferrin receptor (TfR-1) and CD98 heavy chain (CD98hc) has been characterized using techniques incapable of distinguishing between CNS clearance of intact ...

Receptor or TSH binding inhibition tests (TBII) that do not measure stimulatory activity directly but detect factors in the serum specimen that block the binding of a labeled TSH preparation to an ...

The authors demonstrate with convincing evidence the effects of PGE2 on TNF signaling in a well-written manuscript ... Incubation with primary antibodies (diluted 1:1000 in blocking buffer) was ...

Point mutation analysis demonstrated that S448 residue was responsible for the PKA-dependent modulation of Kv2.2. Furthermore, the inhibitory effect of PGE2 on Kv2.2 was blocked by EP2/4 receptor ...

View Full Profile. Learn about our Editorial Policies. Scientists create monoclonal antibodies by cloning a single antibody-producing cell line. In contrast to polyclonal antibodies, monoclonals are ...