Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

The C-terminal 19 amino acids of wild type p53 suppress the p53 response at sublethal doses of radiation. In contrast to cancer cells, mutant p53 activities are not well defined in nonmalignant cells.

The heterozygous 172H/+ genotype has an expanded transcriptome compared to wild type p53. In contrast to cancer cells, mutant p53 activities are not well defined in nonmalignant cells. To examine this ...

A common aromatic shrub that has served as traditional medicine for centuries could point the way toward innovative ...

The aggregate gross proceeds to the Company from the Offering are expected to be approximately $10.0 million, before deducting the placement agent fees and other offering expenses payable by the ...

Elicio Therapeutics, Inc.’s ELTX share price has surged by 13.41%, which has investors questioning if this is right time to ...

Some oncologists suggest that, for certain early cancers not at risk of spreading, the term “cancer” should be avoided.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to function effectively.

A study of men with a family history of prostate cancer has discovered an inherited form of prostate cancer. The inherited ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the ...