Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New ...

Dietary ALAEm supplementation improved sow reproductive performance (total number of piglets born alive, number of piglets weaned, wean weight), serum biochemical indices, placental structure and ...

These pathways promote inflammation and cell damage. At the same time, the gut’s tight junction proteins, such as Junctional Adhesion Molecule (JAM), Occludin, and Claudin, are disrupted, leading to ...

Many bacterial toxins have the ability to enter target cells, most often by using physiological endocytosis pathways, and to modify a specific intracellular target (Table 3). According to the ...

Claudin-18 (CLDN18) is a major component of tight junctions located on the cell membrane surface. CLDN18.1 and CLDN18.2 are specifically expressed in normal lung tissues and gastric mucosa, ...

In addition, epitope masking within the intact TJs of healthy tissue limits off-target binding. Claudin-1 (CLDN1) is upregulated in colorectal cancer (CRC) and promotes therapy resistance and ...

College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, P. R. China College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing ...

NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023 ...

Preclinical data from Baylink's most advanced candidate (BLB-101) will be presented. BLB-101 is an antibody drug conjugate designed to target Claudin 6/9 and deliver the topoisomerase 1 inhibitor, ...

Chronic hemorrhoids, or piles, may cause iron deficiency anemia due to persistent blood loss. Symptoms may develop in severe cases of anemia. They can include tiredness, shortness of breath, and ...

A person may experience swollen feet for several reasons, from hot weather or pregnancy to serious health conditions such as heart disease or a blood clot. Treatment depends on the underlying ...