Results Subcutaneous injection of patient IgG, but not control IgG, resulted in pancreatic and salivary gland injuries. Pancreatic injury was also induced by injecting patient IgG1 or IgG4, with more ...

Polymorphonuclear neutrophils (PMN) represent one of the first lines of defence against invading pathogens and are the most abundant leucocytes in the circulation. Generally described as ...

Background The inflamed bronchial mucosal surface is a profoundly hypoxic environment. Neutrophilic airway inflammation and neutrophil-derived proteases have been linked to disease progression in ...

1Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, Florida. 2Immunology, Genome Regulation and Cell Signaling Program, The Wistar Institute, Philadelphia, Pennsylvania. 3Department of ...

or TTCS-conditioned neutrophils (TCN) at a 1:1 ratio in the presence or absence of a neutralising antibody against human PD-L1 (5 μg/mL) or a control IgG (5 μg/mL) for 24 hours, and were subsequently ...

For decades, neutrophils were viewed as short-lived, transcriptionally inactive cells, mainly engaged in antimicrobial host defense. This notion is changing as recent evidence reveals neutrophil ...