Chronic pain, a common and debilitating condition, often leads practitioners to prescribe opioids in escalating doses.

Neuropathic pain, defined as pain caused by a lesion or disease of the somatosensory nervous system, does not act as a signal to warn the body of damage as acute pain does, and thus it does not have a ...

Background Best current estimates of neuropathic pain (NeuP) prevalence come from studies using various screening detecting pain with probable neuropathic features; the proportion experiencing ...

Treatment with a spinal cord stimulation system reduced pain and restored sensory nerve function in a small cohort of ...

Duloxetine is also an antidepressant, but it belongs to a newer group called SNRIs, which affect certain chemicals in the ...

Vertex Pharma's non-opioid painkiller suzetrigine was unable to perform better than placebo in a phase 2 trial in lumbosacral radiculopathy (LSR), a form of neuropathic back pain, ahead of an FDA ...

Having both aqueous-deficient and evaporative dry eye, corneal pain, or a history of dry eye treatment can worsen quality of life.

which compared AP-325 to placebo in people with post-surgical neuropathic pain, the drug achieved a significant and "clinically meaningful" reduction in the Pain Intensity Numeric Rating Scale (PI ...

Painful diabetic neuropathy was associated with lower quality of life and higher rates of depression and anxiety than painless diabetic neuropathy.