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Each nucleoside triphosphate is made up of three phosphates (represented here by yellow spheres), a deoxyribose sugar (beige rectangle) and one of four bases (differently colored cylinders).
Deoxynucleoside analogues such as 5-aza-2-deoxycytidine (depicted by Z) are converted into the triphosphate inside S-phase cells and are incorporated in place of cytosine into DNA. Ribonucleosides ...
Voth co-authored research published in the Biophysical Journal (January 2025) that investigated the chemical conversion through hydrolysis of the nucleoside Guanosine-5'-triphosphate (GTP) into ...