Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company developing first-in-class therapies for cancer ...

Voth co-authored research published in the Biophysical Journal (January 2025) that investigated the chemical conversion through hydrolysis of the nucleoside Guanosine-5'-triphosphate (GTP) into ...

And, like a turbine, the protein synthesizes energy in the form of adenosine triphosphate (ATP) as it spins, explained Nick Lane, a professor of evolutionary biochemistry at University College ...

If left untreated, human immunodeficiency virus (HIV) almost always will progress to AIDS, even after many years. The immune defenses become compromised and the body is less able to defend itself ...

Though the exact mechanism of action is unclear, it is believed that in patients with Prader-Willi syndrome, diazoxide choline reduces hyperphagia through activation of the adenosine triphosphate ...

Once it enters our cells, it’s phosphorylated into phosphocreatine, an energy substrate that is responsible for regenerating ATP (adenosine triphosphate). During exercise, muscles require ATP as ...

Edited by Donald Ort, University of Illinois at Urbana Champaign, Urbana, IL; received December 10, 2024; accepted January 28, 2025 ...

As illustrated in Figure 2, the model tracks the concentrations of RDV, its intermediate metabolites (IM), and nucleoside monophosphate (NUC ... aim to validate the pharmacokinetics of nucleotide ...

Platinum(II) complexes such as cisplatin, among a few others, are well-known anticancer metal-based drugs approved for clinical use. In spite of their wide acceptance, the respective chemotherapy is ...

They may choose to: Stop your statin therapy Switch you to another type of statin Lower your dose In cases like this, your doctor may recommend you take an adenosine triphosphate-citric lyase (ACL ...