Ndufs2 encodes a core subunit of the mitochondrial complex I (MCI) NADH:ubiquinone oxidoreductase, which contributes to the ubiquinone-binding site of MCI (The Jackson Laboratory; González-Rodríguez ...

Either silencing of MIA40, rescue of complex I, or depletion of NADH through the expression of yeast NADH-ubiquinone oxidoreductase-2 sensitized NDUFA13-KO cells to AIFM1-induced cell death. These ...

CoQ10 may benefit cardiovascular health, fertility, and age-related declining bodily factors. Doctors explain whether you should take it, and potential risks.

Complex I, the NADH-ubiquinone oxidoreductase in Escherichia coli is encoded by the thirteen genes of the nuo operon. It is homologous to the larger enzyme found in mammalian mitochondrial membranes.

NADH:ubiquinone oxidoreductase (complex I) Electron transport chain Rieske protein: Electron transport chain Xanthine oxidase: Purine metabolism, DNA synthesis: Iron deficiency (ID) manifests in 2 ...

Northwest Agriculture & Forestry University has described thiazolecarboxamidine compounds acting as NADH-ubiquinone oxidoreductase (complex I) inhibitors reported to be useful for the treatment of ...

Mitochondria pass through complexes I (CI or NADH: ubiquinone oxidoreductase or NADH dehydrogenase), II (CII, succinic acid: ubiquinone oxidoreductase), III (CIII, ubiquinone: Ferric cytochrome C ...

In contrast, cardiac-specific deletion of PERK aggravates cardiac responses to reperfusion. Mechanistically, the ISR directly targets mitochondrial complexes through translational suppression. We ...

NADH:ubiquinone oxidoreductase (complex I) is a major source of reactive oxygen species in mitochondria and a significant contributor to cellular oxidative stress. Here, we describe the kinetic and ...

NADH: ubiquinone oxidoreductase (complex I) is the first enzyme complex of the respiratory chain. Complex I is a redox-driven proton pump that contributes to the proton motive force that drives ATP ...