Controls were age-matched FVB/N mice. Genotyping was performed as previously described (3). E15.5 embryos and individual kidneys were fixed in 10% formalin. Masson's trichrome was performed using ...

Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...

BACKGROUND: Desmosomal gene variants (DGVs) have been associated with a diverse spectrum of phenotypic manifestations within ...

Crossing TRGL mice with a model of a neurodegenerative disease ... for INK-enhanced clearance of small mHTT species Sequence-based reagent Forward primer for genotyping TRGL: 50-CTT TCC CCA CAG AAT ...

Mouse infestations develop surprisingly fast once these small rodents establish themselves in your living space. Your home offers ideal conditions for these unwanted guests: abundant food, cozy ...

Results: Our results show that genotype, AOF, and sex contributed to AD-like pathology. Aggregation of Ab was heightened in female 5xFAD mice and further increased at peri-AOF, with hippocampal ...

The efficacy of each vaccine candidate to reduce lung bacterial burden depending on the mouse genotype, the vaccine administration route, and the Mtb challenge strain at different time-points was ...

Get Instant Summarized Text (Gist) Increasing levels of the secreted Klotho protein (s-KL) in mice extends lifespan by 15–20% and improves muscle, bone, and cognitive health during aging ...