Monocytes are a principal component of the body’s innate immune system, and the new research looks at how sleep quality ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Poor sleep quality alters immune function, increasing inflammation and disease risk. One night of sleep loss can mimic immune ...

Monocytes are considered to be recruited to the intestine ... resulting in a vicious cycle that contributes to tumourigenesis. We evaluated the function of a microbiota-driven factor in the regulation ...

One key takeaway is that sleep deprivation triggers an increase in nonclassical monocytes (NCMs), immune ... and can impair cognitive function, mood, and overall quality of life.

In the pathogenesis of atherosclerotic diseases, such as coronary artery disease (CAD), monocytes not only serve as the initial sensors of endogenous and exogenous pathogenic factors, but also ...

More information: Fatema Al-Rashed et al, Impact of sleep deprivation on monocyte subclasses and function, The Journal of Immunology (2025). DOI: 10.1093/jimmun/vkae016 ...

It’s also known that poor health outcomes can be driven by chronic inflammation but the direct influence of sleep on circulating immune cells, such as monocytes, is not as well understood.

It's also known that poor health outcomes can be driven by chronic inflammation but the direct influence of sleep on circulating immune cells, such as monocytes, is not as well understood.

Introduction of the variants into healthy cells abolished CCR2 protein expression, and the patients’ own monocytes lacked the receptor. Neehus’s collaborators next set up an in vitro cell migration ...

Monocytes are circulating short-lived macrophage precursors that are recruited on demand from the blood to sites of inflammation and challenge. In steady state, classical monocytes give rise to ...