Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

iPSC differentiated to mesoderm showing expression of mesoderm markers Brachyury (green) and CXCR4 (orange). Credit must be ...

Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10% of people over the age of 65 ...

During the tightly regulated gastrulation, embryonic cells differentiate into the three germ layers—endoderm, mesoderm, and ectoderm—which eventually give rise to all tissues and organs.

Dynamic gene expression in the PSM of vertebrates is critical for the spatial and temporal patterning of somites. Using microarray analysis, we explored in detail, genes that are differentially ...

Extended culture of 2D gastruloids to model human mesoderm development. Nature Methods, 2025; DOI: 10.1038/s41592-025-02669-4 ...

For each of these species, they manually segmented and reconstructed in three dimensions the skeletal structures and muscle groups connecting the head to the trunk, derived from the somitic or ...

Our editorial process produces two outputs: i) public reviews designed to be posted alongside the preprint for the benefit of readers; ii) feedback on the manuscript for the authors, including ...

The lateral plate mesoderm is the developmental origin of the heart, blood vessels, kidneys, connective tissue, as well as major parts of limbs.

A median fin derived from the lateral plate mesoderm and the origin of paired fins. Nature, 2023; DOI: 10.1038/s41586-023-06100-w ...