Cytosolic thiouridylase subunit 2 (CTU2) is an essential and conserved enzyme that modifies tRNA at the wobble position. However, the relationship between CTU2 expression and various cancer types ...

Scientists have developed a new technique to screen engineered enzyme reactions, which could lead to faster and more efficient creation of medicines and sustainable chemicals. Enzymes are proteins ...

In the current study, the researchers focused on PIKfyve, an enzyme that has been identified as a lysosomal target for other cancer types, including blood malignancies. "Even though PIKfyve ...

State Key Laboratory of Green Biomanufacturing, Beijing University of Chemical Technology, Beijing 100029, People’s Republic of China National Energy R&D Center for Biorefinery, Beijing University of ...

“We’re excited to share these enzymes with the genome editing community and to get feedback on their performance as nucleases, base editors, and as other genome editing modalities,” said ...

In their study, authors developed a machine learning algorithm—known as PAMmla—that can predict the properties of about 64 million genome editing enzymes. The work could help reduce off-target ...

State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China School of Food Science and Technology, Jiangnan University, Wuxi 214122, China State Key Laboratory of Food ...