Liu Y, Wang L. Extracellular vesicles targeting non-parenchymal cells: the therapeutical effect on liver fibrosis. eGastroenterology 2024;2:e100040. doi:10.1136/ egastro-2023-100040 ...

Cell Research - Cloning and characterization of a mouse liver-specific gene mfrep-1, upregulated in liver regeneration Skip to main content Thank you for visiting nature.com.

Medically reviewed by Robert Burakoff, MD The liver is an extraordinary organ with a remarkable ability to heal and ...

A new model of liver regeneration: Switch causes mature liver cells to revert back to stem cell-like state. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 06 ...

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 ...

So it makes sense that cells in zone 2, which are sheltered from toxic injuries affecting either end of the lobule, would be in a prime position to regenerate the liver. However, more investigation is ...

Co-cultivation with non-parenchymal liver cells could be used to further improve in vitro liver models, thus reflecting the in vivo situation closer than current state of the art models.

"Cutting-edge technologies have allowed us to study human liver regeneration in high definition for the first time, facilitating the identification of a cell type that is critical for liver repair ...

Research published in 2023 indicates that the kidneys, for example, can also regenerate to an extent. Stem cells in the kidney can form new kidney cells, but not to the same degree as in the liver.

image: Hepatocytes are reprogrammed into biliary cells upon liver injury. Immunofluorescence analysis of yellow fluorescent protein-expressing mouse hepatocytes at 4 weeks after toxin-induced injury.