Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

The study further examines the interplay between ubiquitination and key signaling pathways, including Notch, Wnt/β-catenin, Hedgehog, and Hippo-YAP, which regulate stem-like properties in cancer ...