A research team at the University of Münster has investigated for the first time how the confrontation of bacteria with hosts ...

In the quest to design vaccines that better help the body's immune system fight disease, scientists are always looking for more tools for their arsenal.

Groundbreaking study reveals TR1 cells' crucial role in immune response to malaria, paving way for new vaccines and drugs.

Ingelheim, Germany, 22 May 2025 – Boehringer Ingelheim today announced that new clinical data from two early-stage trials targeting the signal regulatory protein α (SIRPα) innate immune checkpoint ...

The immune system has two main arms: innate and adaptive. The innate immune system recognizes broad molecular patterns, such as molecules that certain RNA viruses generate as they replicate. It is ...

RAR is a synthetic-modified RNA motif derived from the hepatitis C virus genome that is specifically recognized by RIG-I and induces innate immune activation, including production of interferon ...

Cholesterol metabolism is associated with innate immune responses; however, the underlying mechanism remains unclear. Here, we perform chemical screening to isolate small molecules influencing RIG-I ...

TRIM25 is a protein that is important in the innate immune response against RNA viruses, such as influenza viruses, coronaviruses, or Zika virus. New research has shown how TRIM25 binds to viral ...

The SKIV2L cytoplasmic RNA exosome limits the dsRNA-induced innate immune response. The RNA helicase activity of SKIV2L is essential for this effect.

For example, the innate immune receptor TLR7 is stimulated by viral RNA. We can picture viral RNAs as long threads of molecules, which are much too large to be recognized as ligands for TLR7. This is ...

For example, the innate immune receptor TLR7 is stimulated by viral RNA. We can picture viral RNAs as long threads of molecules, which are much too large to be recognized as ligands for TLR7.