pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl ... structural modeling to show that the enzyme [MoCu]-CO dehydrogenase interacts ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Researchers from the University of Bayreuth and the Max Planck Institute for Dynamics and Self-Organization in Göttingen have investigated the movement patterns of unicellular, hydrogen-producing ...

RedHill Biopharma Ltd (RDHL) reported its Q1 2022 earnings, revealing a decrease in net revenues to $18.2 million from $22.1 million in the previous quarter. Despite this, the company achieved a gross ...

Interface-pLDDT is the best indicator of model docking quality ... capturing backbone conformational changes with our induced-fit protocol ReplicaDock2.0 2. We named the protocol AlphaRED ...

Moreover, when measured separately, comparing the activity of both isoforms requires normalizing ... The fold change data in the screen were calculated as the top/bottom of each fit. The optimal trio ...