The drug candidate – called vorasidenib – is a dual inhibitor of mutated IDH1 and IDH2, which is being developed for a hard-to-treat form of brain cancer called glioma. It was acquired by ...

Scientists from Adelaide and the United States have found a surprising connection between a rare type of arthritis and gene ...

The genetic testing results showed mutations in KRAS, PIK3CA, TP53, Isocitrate Dehydrogenase 2 (IDH2), CREB Binding Protein (CREBBP), Colony Stimulating Factor 1 Receptor (CSF1R), GATA Binding Protein ...

No mutations were detected in IDH1/IDH2, ATRX, BRAF, P53, H3F3A, or the TERT promoter. Combining the above test results with morphological, molecular, and immunohistochemical examinations, the ...

The integration of targeted therapies into neuro-oncology is revolutionizing the management of primary CNS malignancies. Advances in sequencing technologies and the incorporation of molecular ...

Retrospective Analysis of BRCA-Altered Uterine Sarcoma Treated With Poly(ADP-ribose) Polymerase Inhibitors Chondrosarcomas are rare cancers of cartilage with limited systemic therapy options. To ...

HONG KONG and SHANGHAI and FLORHAM PARK, N.J., March 19, 2025 (GLOBE NEWSWIRE) -- HUTCHMED (China) Limited (“HUTCHMED”, the “Company” or “we”) (HKEX: 13 ...

SEATTLE — For decades, Washington women’s rowing has been one of the most successful programs in the sport, winning 12 national titles in the past 50 years. But before 1975, it wasn’t even a ...

A young British woman who used to drink 12 cups of coffee a day and quit because of some caffeine withdrawal symptoms like severe headaches was diagnosed with grade three oligodendroglioma—a type of ...