(RTTNews) - Biopharmaceutical company Ligand Pharmaceuticals, Inc. (LGND), while reporting a loss in its fourth quarter, compared to prior year's profit, on Thursday confirmed fiscal 2025 forecast.

College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, No. 26 Hexing Road, Harbin 150040, China ...

Department of Chemistry, Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education), Tsinghua University, Beijing 100084, People’s Republic of China Department of Chemistry, ...

Another way is to add a targeting ligand to the polymer nanoparticles so that they ... This polymer can serve as a prodrug polymeric nanocarrier to load a variety of hydrophobic drugs, such as BMN673.

Despite their hydrophobic nature, Wnt proteins exert their function over long distances to induce paracrine signalling. Recent studies have identified several factors involved in Wnt secretion; ...

Stabilizing hydrophobic interactions occur between the side chains of Y204 and P461 with the aryl moiety of 3b. Additionally, the side chain of H263 is positioned such that the Cε2 carbon atom ...

The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

Some vitamins (e.g., vitamin B family and vitamin C) are water-soluble, whereas others (e.g., vitamins A, D, E, and K) are hydrophobic. Both hydrophilic and hydrophobic vitamins and their metabolites ...

The ensembles revealed that, while most proteins display a well-ordered core, some proteins exhibit a ‘molten core’ likely supporting functionally important dynamics in ligand binding, enzyme activity ...

We demonstrate a major structural change on the binding of an activating ligand to a KTN-domain protein. Analysis of the regulatory interactions suggests strategies to disrupt pathogen potassium and ...