14 Centre for Liver and Gastroenterology research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK 15 NIHR Biomedical Research Centre, University of Birmingham and ...
Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, focuses here on CYP genes, haplotypes, and their ...
A study conducted by Prof. Thai-Yen Ling at National Taiwan University underscores the potential of small extracellular ...
Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...
Scientists at Massachusetts General Hospital have revealed how chronic liver injury alters hepatic stellate cells (HSCs), triggering the formation of fibrotic scarring in the liver. The researchers ...
St. Patrick’s Day has passed. If your liver is still functional (meaning you didn’t down too many Salty Dogs) and you're ...
MOE Key Laboratory of Bioinformatics, State Key Laboratory of Molecular Oncology, Beijing Frontier Research Center for Biological Structure, School of Pharmaceutical Sciences, Tsinghua University, ...
Here, we investigated the metabolic stability and enzyme kinetics of carboxylesterase-mediated hydrolysis and cytochrome P450 (CYP)-mediated oxidation of EA and EB in human liver microsomes (HLMs). We ...
Cytochrome P450 (CYP) enzymes are a large class of heme-thiolate protein superfamily ... Among multiple CYP isoforms, CYP3A4 is mainly expressed in the liver and intestines of adult human, and has a ...
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