gut.bmj14d
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Results We showed that hypoxia enhanced the stemness of HCC cells and hepatocarcinogenesis through enhancing HIF-1α deSUMOylation by SENP1 and increasing stabilisation and transcriptional activity of ...
eLife15d
STAMBPL1 activates the GRHL3/HIF1A/VEGFA axis through interaction with FOXO1 to promote angiogenesis in triple-negative breast cancer
Fang et al. find that in cell line models of TNBC, STAMBPL1 promotes expression of the transcription factor HIF-1a and its downstream target VEGF, with the consequence of stimulating neo-angiogenesis ...
Sports Illustrated19d
Final state bowling champions crowned on last day
The Top 8 finishers from the Class 3A individual state bowling championships. / X/IHSAA The final four state bowling championships were handed out on Wednesday on the third and final day of action ...
The EMBO Journal21d
Ubiquitin is directly linked via an ester to protein-conjugated mono-ADP-ribose
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The prevailing view on post-translational ...
al.com22d
Class 1A Girls semifinals: Ace Austin’s triple-double leads Spring Garden past R.C. Hatch
Ace Austin piled up 32 points, 11 rebounds and 11 assists in Monday’s Class 1A semifinal win over R.C. Hatch. The Spring Garden star had one favorite part of her triple-double. “I don’t ...
Irish Daily Mirror24d
Tipperary defeat Cork to stay top of Division 1A in the Allianz Hurling League
Tipperary maintained their position at the top of Division 1A with a win over Cork in the Allianz Hurling League. The hosts looked impressive throughout and they took a halftime lead of 1-12 to 1 ...
Sports Illustrated25d
TEXAS UIL BOYS BASKETBALL AREA PLAYOFF CLASS 1A-6A SCOREBOARD
State finals will be held March 6-8 at The Alamodome in San Antonio. Last season's boys state champions were Jayton (1A), Lipan (2A), Hitchcock (3A), Oak Cliff Faith Academy (4A), Lancaster (4A ...
South Bend Tribune26d
IHSAA Class 1A girls basketball northern semistate: How each of the four teams can win a title
How much experience matters might dictate who wins the IHSAA Class 1A North girls basketball semistate championship Saturday at LaPorte High School. Two of the programs left, Marquette Catholic ...
KVOE27d
KSHSAA releases sub-state brackets for Classes 1A-DI and 1A-DII
Sub-State brackets have been released for Class 1A-DI and 1A-DII. In Class 1A-DI, area teams are either a part of the Centralia region or the Canton-Galva region. Area schools in Class 1A-DII are a ...
The EMBO Journal27d
Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The adipokine apelin has been directly ...
KMA Land27d
1A State Wrestling Day 1: 16 KMAlanders reach quarterfinals
(Des Moines) -- Sixteen of the 58 KMAland wrestlers who qualified for the Class 1A State Tournament still have their championship dreams alive after the first day. The group hails from 10 ...