A novel therapeutic showed significant promise in slowing aortic valve calcification, potentially extending time until or eliminating need for transcatheter or surgical intervention for stenosis, ...

Ataciguat, part of the sGC activator drug class previously studied in angina and peripheral arterial disease, both with negative results, restores nitric oxide signaling by binding to its receptor ...

HIF-1α interfering agent cobalt chloride (CoCl2) and guanylate cyclase activator (Lificiguat, YC-1) were added respectively, with a control group established accordingly. Sperm motility (using ...

Nitric oxide (iNO) is selective pulmonary vasodilation and is delivered to the patient via mechanical ventilation after dilution with an oxygen/air mixture nitric oxide delivery system. Nitric oxide ...

Vericiguat, already available under the brand name Verquvo by Bayer, is a soluble guanylate cyclase stimulator. It is specifically designed to help patients with chronic heart failure with reduced ...