How do activation of glucocorticoid receptor-deficient T-cells and dysregulation of COX-2 activity cause mortality? Histological analyses of TGRKO and control mice treated with antibody to CD3ε ...
This sensitivity is due to its high concentration of glucocorticoid receptors, the "stress hormones" which are present in high levels in families exposed to war. The largest and most recent study ...
Adrenocorticotropic hormone (ACTH) released by the pituitary gland evokes glucocorticoid synthesis by adrenal cortex. CRF and ACTH production is inhibited by glucocorticoid feedback. Norepinephrine is ...
Direct actions of GCs on immune cells were suggested to suppress inflammation. Objectives Define the role of the glucocorticoid receptor (GR) in stromal cells for suppression of inflammatory arthritis ...
Learn more about eLife assessments Interactions between NopT and NFR1 and NFR5 were detected using Split–YFP assay (A) and (B), Split–LUC (C) and co–IP (D) assays in N. benthamiana. (A) and (B). nYFP ...
In this study we deployed multiple assays to study the pharmacology of standard kappa opioid receptor ligands with differing pharmacological properties then to characterize and compare two novel ...