This fundamental article significantly advances our understanding of FGF signalling, and in particular highlights the complex modifications affecting this pathway. The evidence for the authors' claims ...

Figure 2: Fgf8 expression and alkaline phosphatase activity in embryos bearing mutant alleles of Fgf8. The loss of mesenchyme and AER in the anterior forelimb buds of conditional mutants can be ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...