New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in ...

SEBiotic® (Bacillus coagulans LBSC), produced by Specialty Enzymes & Probiotics, is a spore-forming probiotic shown to be effective and safe in the treatment of drug-induced constipation associated ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Pfizer has announced the decision to discontinue the development of danuglipron, an oral glucagon-like peptide-1 (GLP-1) ...

Shares of Novo Nordisk, Eli Lilly, Structure Therapeutics and Viking Therapeutics gain as PFE abandons development of its ...

Pfizer is stopping development of its experimental oral GLP-1 drug for obesity, the company announced Monday, after a patient ...

A new international study reveals a possible connection between GLP1 receptor agonists—used in drugs like Ozempic—and ...

Pfizer has ceased development of its oral GLP-1 weight loss drug candidate, danuglipron, after a study participant ...

Pfizer has axed its oral GLP-1 asset danuglipron after one patient had potential drug-induced liver injury in a phase 1 trial ...

SCN4B might be a key puzzle piece toward uncovering drug-induced maladaptive plasticity that drives prepotent ... Research ...

A new study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.