Each enzyme molecule has a special place called the active site where another molecule, called the substrate, fits. The substrate goes through a chemical reaction and changes into a new molecule ...

However, it is safe to say that no enzyme is perfect in the sense of catalyzing only a single reaction with a single substrate. For enzymes such as P450s and glutathione S-transferases that are ...

A continued increase in pH results in a sharp decrease in activity as the enzyme’s active site changes shape. It is now denatured. As the substrate concentration increases so does the rate of ...