Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short.

However, until now there has been a lack of active compounds that specifically switch off/selectively inhibit only these two ...

Catalytic conversion of waste CO2 into value-added fuels and chemicals offers unprecedented opportunities for both ...

A new study reveals a surprising mechanism by which itaconate inhibits the active site of a peroxiredoxin enzyme to amplify redox signalling and the type I interferon response in macrophages.

Enzyme mechanisms are the chemical transformations ... linked variants to illuminate how the [4Fe-4S] cofactor and active site are allosterically connected with significance for fidelity and ...

Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("Acurx" or the "Company"), a late-stage biopharmaceutical company developing a new class of small molecule antibiotics for difficult-to-treat bacterial ...

SandboxAQ, a company using quantum-based algorithms and simulations to train AI models, is expanding its existing ...

Rising demand, supply concerns and global trade tensions led to urea price rises of over £40/t during March, with some ...

SandboxAQ today announced a collaboration with NVIDIA across biopharma, chemicals, advanced materials, financial services, cybersecurity, navigation, and medical imaging. SandboxAQ, a member of ...

A novel application for a compound called ML233 has shown promising results for inhibiting melanin production, offering ...