Harliku is the only FDA-approved drug for alkaptonuria, a rare condition characterized by skin discoloration, arthritis and heightened risks of heart failure and stroke.

For many years, astrocytes were seen as simple support cells in the brain. Today, that picture is changing fast.

Health experts warn that this weekday-fasting, weekend-bingeing cycle can disrupt the gut microbiome, trigger digestive ...

If successful, their 2030 plan will be four 350 cubic-meter reactors capable of processing 45,000 metric tons of PET plastic ...

Memorial Sloan Kettering Cancer Center researchers have identified a metabolic switch that determines whether intestinal stem ...

The first product from BiomEdit—engineered microbes that protect broiler chickens from necrotic enteritis—could hit the ...

Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme, as a third structural component of ...

“Enzymes are the hardest working molecules in ... “No company has all the solutions and every product has a life cycle that ages with diminishing returns and needs to be refreshed or replaced.” ...

which causes upregulation of the urea cycle and putrescine-to-GABA production. This leads to elevated production of GABA and toxic H2O2, which inhibits neuronal signaling and causes neuronal death ...

They strike women more often than men. Blujepa works by interfering with two enzymes that bacteria need to copy themselves. Because its mechanism of action is targeted, it may cut down on the ...

Researchers have discovered that an enzyme can serve as an ideal target ... has evolved unique metabolic pathways to cope with its enzootic life cycle, some of which are specific and ideal targets ...

“This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle and cell proliferation,” said senior author Dylan Taatjes, a professor in the Department of ...